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Bio Techne

Bio-Techne is a global developer, manufacturer, and supplier of high-quality reagents, analytical instruments, and precision diagnostics. Whether you’re at the cutting edge of academic research, translating basic discoveries into therapeutic leads, or at a facility that requires the highest level of diagnostic testing, our award-winning tools and solutions empower scientists and clinicians to achieve reproducible and consistent results. Choosing Bio‑Techne means having confidence that every solution you use will help move you towards better answers.

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Antibodies

Antibodies are essential tools for biomedical research as they allow researchers to identify specific proteins or molecules. Our catalog of over 425,000 antibodies from our R&D Systems™ and Novus Biologicals™ brands have been validated for specificity and reproducibility in over 25 species for more than 15 applications, ensuring that you will find one for your research needs.

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Your unique cell cultures require a consistent foundation whether you are using classical or specialty media, sera, supplements, and matrices. Thorough cell characterization is also critical to determine if the phenotype is what you need for your particular application.

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Have confidence in your results with R&D Systems™ rigorously validated and tested ELISA kits. As the most published ELISA supplier, with more than 30 years of experience designing and optimizing quantitative immunoassays, you can trust that you have publishable, reproducible data every time.

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ELISA Kits

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Fluorescent and bioluminescent reagents enable highly sensitive and selective visualization of biological events, from single molecule tracking in vitro through to in vivo imaging. Discover our exclusive range of fluorescent probes, indicators, dyes, and stains.

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Recombinant Proteins

Bio-Techne offers over 5,000 R&D Systems™ bioactive recombinant proteins spanning 35 species and multiple research areas. Our portfolio includes cytokines and growth factors, proteins for studying immuno-oncology targets, enzymes, and animal-free and GMP-grade proteins, as well as custom protein development services and more.

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Recombinant Proteins

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Small molecules and peptides can be used in all stages of biological and biomedical research. Bio-Techne’s unique collection of small molecules and peptides includes high quality, novel, and innovative compounds such as enzyme inhibitors, ion channel modulators, GPCR agonists and antagonists, fluorescent probes and dyes, and molecular biology tools.

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Related Resources

Optimizing Organoid Culture Conditions:

Optimizing Organoid Culture Conditions

An application note demonstrating the value of R&D Systems™ proteins for achieving robust, reproducible organoid culture conditions
Filename
23227_bio_techne_optimizing_organoids_Fisherised_v2.pdf
Size
1 MB
Format
application/pdf
Realize Your Protein and Cell Potential

Realize Your Protein and Cell Potential

Realize your protein and cell potential
Filename
23227_bio_techne_realize_protein_Fisherised.pdf
Size
3 MB
Format
application/pdf
Organ-on-a-Chip Technology:

Organ-on-a-Chip Technology

Progress, challenges, and an exciting future
Filename
23227_bio_techne_organ_on_a_chip_technology_progress_Fisherised.pdf
Size
326 KB
Format
application/pdf

Fisher Scientific Europe Announces a New Distribution Agreement with Bio-Techne in Europe

Paris, France 01-05-2024

 

Thermo Fisher Scientific, a leading provider of laboratory products and services, is pleased to announce a significant milestone in its commitment to providing cutting-edge solutions to its customers. Effective May 1, 2024, Thermo Fisher will enter into a strategic European distribution agreement with Bio-Techne (NASDAQ: TECH), a global life sciences company providing innovative tools and bioactive reagents for the research and clinical diagnostic communities.

This partnership marks an important collaboration between two industry leaders in the fields of scientific research, diagnostics, and biotechnology. Under this agreement, Thermo Fisher, through the Fisher Scientific channel, Europe, will distribute Bio-Techne's extensive portfolio of innovative products, including antibodies, proteins, immunoassay kits, reagents and enzymes to laboratories and research institutions across Europe.

"We are thrilled to forge this partnership with Bio-Techne, a company renowned for its pioneering advancements in the life sciences industry," said Claire Wallace, President, Fisher Scientific channel, Europe. "By adding Bio-Techne's high-quality products to our comprehensive portfolio, we aim to further empower scientists and researchers with the tools they need to drive breakthrough discoveries and advancements in healthcare."

Bio-Techne's state-of-the-art products are designed to accelerate research and improve outcomes in areas including cell and gene therapy, immunology, neuroscience, and more. With this collaboration, Thermo Fisher reinforces its commitment to providing customers with access to the latest technologies and expertise, ultimately advancing scientific knowledge and improving human health.

"We are excited to partner with Thermo Fisher to expand the reach of our products and services throughout Europe," said Kim Kelderman, Bio-Techne’s President and Chief Executive Officer. "By leveraging the Fisher Scientific Channel's extensive European distribution network and industry expertise, we aim to enhance support for researchers and accelerate scientific discoveries that address some of the most pressing challenges in healthcare today."

This distribution agreement underscores Thermo Fisher's dedication to fostering innovation and collaboration within the scientific community. Through strategic partnerships with leading companies like Bio-Techne, Thermo Fisher continues to strengthen its position as a trusted partner for researchers and laboratories across Europe.

About Bio-Techne

Bio-Techne Corporation (NASDAQ: TECH) is a global life sciences company providing innovative tools and bioactive reagents for the research and clinical diagnostic communities. Bio-Techne products assist scientific investigations into biological processes and the nature and progress of specific diseases. They aid in drug discovery efforts and provide the means for accurate clinical tests and diagnoses. With thousands of products in its portfolio, Bio-Techne generated over $1.1 billion in net sales in fiscal year 2023 and has approximately 3,100 employees worldwide.

 

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1 – 15 of 400,898 results
1

Novus Biologicals™ Recombinant Human HMGB1/HMG-1 His (C-Term) Protein

Recombinant Protein

Purity or Quality Grade >95% by SDS-PAGE and HPLC
Molecular Weight (g/mol) 26 kDa
Gene Symbol HMGB1
Endotoxin Concentration Less than 1 EU/ug of HMGB1/HMG-1 as determined by LAL method.
Storage Requirements Store at -20°C to -70°C as supplied. After reconstitution, store at 2°C to 8°C for 1 month and at -20°C to -70°C for long term storage. Avoid repeated freeze-thaw cycles.
Concentration LYOPH
For Use With (Application) PAGE
Protein HMGB1/HMG-1
Accession Number P09429, P09429, P09429
Gene Alias Amphoterin, high mobility group box 1, High mobility group protein 1, high mobility group protein B1, high-mobility group (nonhistone chromosomal) protein 1, high-mobility group box 1, HMG-1, HMG1DKFZp686A04236, HMG3, SBP-1, Sulfoglucuronyl carbohydrate binding protein
Gene ID (Entrez) 3146
Formulation Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Research Category Cellular Markers, Chromatin Research, Neuroscience
Reconstitution Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at <-20°C.
2

HIF-1 alpha Antibody, Novus Biologicals™

Rabbit Polyclonal Antibody has been used in 241 publication

3

Novus Biologicals™ Cannabinoid R1/CB1/CNR1 Antibody (nimacimab) - Humanized, Novus Biologicals™

Human Monoclonal Antibody

Content And Storage Store at -20°C in powder form. Store at -80°C once reconstituted.
Target Species Human
Host Species Human
Conjugate Unconjugated
Applications Flow Cytometry,ELISA,Functional Assay
Form Purified
Isotype IgG4
Gene Accession No. Q96F85
Research Discipline Cancer, GPCR, Neuroscience, Neurotransmission, Vision
Antigen Cannabinoid R1/CB1/CNR1
Regulatory Status RUO
Purification Method Protein A purified
Gene Alias CANN6CB1R, cannabinoid receptor 1 (brain), CB1A, CB1K5, CB-RCB1cannabinoid receptor 1, central cannabinoid receptor, CNR
Gene ID (Entrez) 1268
Formulation Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Immunogen CB1/ CNR1
Classification Monoclonal
Reconstitution Reconstitute with sterile, distilled water to a final concentration of 1 mg/mL. Gently shake to solubilize completely. Do not vortex.
Primary or Secondary Primary
Clone nimacimab
4

Novus Biologicals™ Frizzled-9 Antibody (vantictumab) - IgG2SA, Novus Biologicals™

Human Monoclonal Antibody

Content And Storage Store at -20°C in powder form. Store at -80°C once reconstituted.
Target Species Human
Host Species Human
Conjugate Unconjugated
Applications Flow Cytometry,ELISA,Functional Assay
Form Purified
Isotype IgG2
Research Discipline GPCR, Growth and Development, Neuronal Cell Markers, Signal Transduction, Wnt Signaling Pathway
Antigen Frizzled-9
Regulatory Status RUO
Purification Method Protein A purified
Gene Alias CD349, CD349 antigen, frizzled (Drosophila) homolog 9, frizzled homolog 9 (Drosophila), frizzled-9, fz-9, FZD3fzE6, FzE6, hFz9
Gene ID (Entrez) 8326
Formulation Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Immunogen FZD
Classification Monoclonal
Reconstitution Reconstitute with sterile, distilled water to a final concentration of 1 mg/mL. Gently shake to solubilize completely. Do not vortex.
Primary or Secondary Primary
Clone vantictumab
5

Caspase-3 Antibody - (active/cleaved), Novus Biologicals™

Rabbit Polyclonal Antibody has been used in 48 publications

Content And Storage Store at -20C. Avoid freeze-thaw cycles.
Target Species Human,Mouse,Rat,Gerbil
Host Species Rabbit
Conjugate Unconjugated
Applications Western Blot,Flow Cytometry,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunoprecipitation,Immunohistochemistry (Paraffin),Immunohistochemistry (Frozen),Immunoblot
Form Antisera
Isotype IgG
Research Discipline Apoptosis, Cancer, Caspases, Phospho Specific
Antigen Caspase-3
Gene Symbols CASP3
Regulatory Status RUO
Purification Method Unpurified
Dilution Western Blot 1:1000-1:2000, Flow Cytometry reported in scientific literature (PMID 28287161), Immunohistochemistry, Immunocytochemistry/Immunofluorescence reported in scientific literature (PMID 29963272), Immunoprecipitation 1:50-1:200, Immunohistochemistry-Paraffin 1:1000-1:5000, Immunohistochemistry-Frozen reported in scientific literature (PMID 29864441), Immunoblotting reported in scientific literature (PMID 27912032), Flow (Intracellular) reported in scientific literature (PMID 24804954)
Molecular Weight of Antigen 31.7 kDa
Gene Alias Apopain, apoptosis-related cysteine protease, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, CPP-32, CPP32B, CPP32SREBP cleavage activity 1, Cysteine protease CPP32, EC 3.4.22, EC 3.4.22.56, PARP cleavage protease, procaspase3, Protein Yama, SCA-1, Yama
Gene ID (Entrez) 836
Formulation Neat whole antisera with 0.05% Sodium Azide
Immunogen This Caspase-3 Antibody - (active/cleaved) was developed against catalytically active human caspase-3 protein.
Classification Polyclonal
Primary or Secondary Primary
Test Specificity Preferentially detects active caspase-3 (large subunit: ∼14-21 kDa, and small subunit: ∼10 kDa). However, it may also detect pro-caspase-3 (∼32 kDa) in some cell or tissue systems. Nuclear immunostaining of caspase-3 is considered be an indication of active/cleaved caspase-3.
7

Factor VIII Antibody - BSA Free, Novus Biologicals™

Rabbit Polyclonal Antibody has been used in 4 publications

Antigen Factor VIII
Gene Symbols F8
Regulatory Status RUO
Purification Method Affinity Purified
Target Species Mouse,Rat
Host Species Rabbit
Applications Western Blot,Immunofluorescence,Immunohistochemistry (Paraffin)
Immunogen A synthetic peptide made to a C-terminal portion of human Factor VIII (between amino acids 2100-2250) [UniProt P00451]
11

CD44 Antibody (Hermes-1) - Azide and BSA Free, Novus Biologicals™

Rat Monoclonal Antibody has been used in 4 publications

Gene Symbols CD44
Content And Storage Store at -20C. Avoid freeze-thaw cycles.
Purification Method Protein G purified
Dilution Western Blot 1:1 - 1:100, Flow Cytometry 1:10 - 1:1000, ELISA 1:100 - 1:2000, Immunohistochemistry 1:10 - 1:2000, Immunocytochemistry/Immunofluorescence 1:10 - 1:200, Immunoprecipitation 1:10 - 1:50, CyTOF-ready, Neutralization
Classification Monoclonal
12

alpha Tubulin Antibody (DM1A) - BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody has been used in 89 publications

Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Target Species Human,Mouse,Rat,Pig,Avian,Bovine,Canine,Chicken,Chinese Hamster,Drosophila,Fungi,Guinea Pig,Goat,Hamster,Parasite,Monkey,Primate,Rabbit,Xenopus species,Yeast
Host Species Mouse
Conjugate Unconjugated
Applications Western Blot,Flow Cytometry,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunoprecipitation,Immunohistochemistry (Paraffin),Immunohistochemistry (Frozen),Immunomicroscopy,CyTOF
Form Purified
Isotype IgG1 κ
Research Discipline Cell Biology, Cell Cycle and Replication, Cytoskeleton Markers, Loading Controls, Neuroscience
Concentration 1.0 mg/mL
Antigen alpha Tubulin
Gene Symbols TUBA1A
Regulatory Status RUO
Purification Method Protein G purified
Dilution Western Blot 1:5000, Simple Western 1:50, Flow Cytometry 1 ug per million cells, Immunohistochemistry 1:100-1:500, Immunocytochemistry/Immunofluorescence 1:50000-1:100000, Immunoprecipitation 1:50-1:100, Immunohistochemistry-Paraffin 1:100-1:500, Immunohistochemistry-Frozen 1:100-1:500, Immunomicroscopy, Flow (Intracellular), CyTOF-ready
Molecular Weight of Antigen 50 kDa
Gene Alias alpha tubulin loading control, alpha tubulin monoclonal, Alpha-tubulin 3, B-ALPHA-1, DM1A, DM1A anti-tubulin, dm1a monoclonal, DM1a tubulin, FLJ25113, hum-a-tub1, hum-a-tub2, LIS3, TUBA1 monoclonal, TUBA3, tubulin alpha-1A chain, Tubulin alpha-3 chain, Tubulin B-alpha-1, tubulin monoclonal, tubulin, alpha 1a, tubulin, alpha 3, tubulin, alpha, brain-specific
Gene ID (Entrez) 7846
Immunogen This alpha Tubulin Antibody (DM1A) was developed against native chicken brain microtubules.
Classification Monoclonal
Primary or Secondary Primary
Test Specificity This alpha Tubulin Antibody (DM1A) does not cross-react with beta Tubulin.
Clone DM1A
14

Carbonic Anhydrase IX/CA9 Antibody - BSA Free, Novus Biologicals™

Rabbit Polyclonal Antibody

Gene Symbols CA9
Dilution Western Blot 1 - 3 ug/ml, Simple Western 1:50, Flow Cytometry 1:1000, ELISA reported in scientific literature (PMID 19963243), Immunohistochemistry 1:200 - 1:500, Immunocytochemistry/Immunofluorescence 2 - 5 ug/ml, Immunoprecipitation 1:10 - 1:500. Use reported in multiple pieces of scientific literature, Immunohistochemistry-Paraffin 1:200 - 1:500, Immunohistochemistry-Frozen 1:200 - 1:500, Immunoblotting, Gel Super Shift Assays, Proximity Ligation Assay, Microarray reported in scientific literature (PMID 31955345), Chromatin Immunoprecipitation (ChIP) 1:10-1:500, Dual RNAscope ISH-IHC 1:1000
Molecular Weight of Antigen 55 kDa
Gene Alias CA-IX, CAIXcarbonic anhydrase 9, Carbonate dehydratase IX, carbonic anhydrase IXpMW1, carbonic dehydratase, EC 4.2.1.1, G250, Membrane antigen MN, MNRCC-associated antigen G250, P54/58N, RCC-associated protein G250, Renal cell carcinoma-associated antigen G250

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