Popular Organic Reactions

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To help you run some of the most important reactions in synthetic organic chemistry, links to a collection of practical reference information are provided below. Each section contains a basic reaction description, reference reaction protocols, literature references and examples.

For your convenience, all the chemicals you need to set up and run each reaction are also listed, making it so easy to find them that you can get from the web back to the lab in five minutes.

Chemical Information

Chemical

Suzuki-Miyaura Cross-Coupling Reaction

Carbon-c cross-coupling represents one of the biggest revolutions in organic chemistry and such reactions are currently some of the most common in synthetic organic chemistry.

Chemical

Amine Protection / Deprotection

The BOC (tert-butyloxycarbonyl) protecting group, chemically a di-tert-butyl dicarbonate (Boc2O), is probably the most common amine protecting group in non-peptide chemistry. The reaction conditions for the amine protection are quite flexible...

Chemical

Aromatic Nucleophilic Substitution

Aromatic nucleophilic substitution is an extremely useful tool for the functionalization of aryl compounds. It has been around since the early 1950’s and is still very commonly used in organic synthesis.

Chemical

Amination

Amines are incredibly useful intermediates and they are a key functionality of most biologically active molecules. In modern organic synthesis practice, the most common reactions to form C-N bonds, besides the synthesis of amides...

Chemical

Amide Synthesis

The direct coupling between a carboxylic acid and an amine competes with acid/base proton exchange and is hardly a suitable choice in synthetic chemistry. The most common strategy is the conversion of the acid to an activated form...

Chemicals Information

Resources

Key Named Reactions in Organic Chemistry

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